Power production from wind energy has been increasing over the past decades, with more areas being used as wind farms and larger wind turbines (WTs) being built. As the awareness of the impact of wind energy on the environment and human health as also increased, so has the interest in developing fast turnaround WT blade design frameworks capable of predicting both aerodynamic and aeroacoustic performance. In this paper, the development of such framework is described and the results of single and multi operating point optimizations of the blades of the commercial AOC 15/50 WT are presented and discussed. Noise reductions of up to 9.8% were achieved, with a cost of only 1% in energy production.